2-AMINO-4-HYDROXY-7H-PYRROLO[2,3-DPYRIMIDINE]
7-Deazaguanine
CAS: 7355-55-7
Molecular Formula: C6H6N4O
2-AMINO-4-HYDROXY-7H-PYRROLO[2,3-DPYRIMIDINE] - Names and Identifiers
2-AMINO-4-HYDROXY-7H-PYRROLO[2,3-DPYRIMIDINE] - Physico-chemical Properties
| Molecular Formula | C6H6N4O |
| Molar Mass | 150.14 |
| Density | 1.87±0.1 g/cm3(Predicted) |
| Melting Point | >230°C (dec.) |
| Boling Point | 452.7°C at 760 mmHg |
| Flash Point | 227.6°C |
| Solubility | Soluble in N,N-Dimethylformamide, Dimethyl sulfoxide. |
| Vapor Presure | 2.2E-08mmHg at 25°C |
| Appearance | crystalline |
| Color | tan |
| pKa | 10.83±0.20(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.89 |
2-AMINO-4-HYDROXY-7H-PYRROLO[2,3-DPYRIMIDINE] - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. S60 - This material and its container must be disposed of as hazardous waste. |
| UN IDs | 2811 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
2-AMINO-4-HYDROXY-7H-PYRROLO[2,3-DPYRIMIDINE] - Introduction
7-Deazaguanine, also known as 7-deazaguanine, is an organic compound with a special structure. Its chemical formula is C5H5N5O and its relative molecular mass is 163.13.
In terms of properties, 7-deazaguanine is a white crystalline solid, insoluble in water and soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF). It is stable under acidic conditions, but decomposes under alkaline conditions.
7-Deazaguanine plays an important role in biology, especially in the construction and modification of nucleic acids. It is a special base that can be used by some bacteria and fungi to replace adenine (adenine) to form different nucleosides (nucleoside) in RNA and DNA. 7-Deazaguanine also has applications in the development of fungal antibiotics and anticancer drugs.
In the preparation method, 7-deazaguanine can be prepared by chemical synthesis. A common method is to synthesize the target product by tandem reaction using the corresponding pyrrole reagent as the starting material.
In terms of safety information, due to the professional application of 7-deazaguanine in the laboratory, the relevant toxicity and safety information has not been fully studied and understood. Therefore, when using or handling, it is necessary to follow the corresponding safety procedures and take necessary personal protective measures, such as wearing gloves and protective glasses. When handling chemicals, direct contact with the skin and inhalation of its dust should be avoided.
In terms of properties, 7-deazaguanine is a white crystalline solid, insoluble in water and soluble in some organic solvents such as dimethyl sulfoxide (DMSO) and dimethyl formamide (DMF). It is stable under acidic conditions, but decomposes under alkaline conditions.
7-Deazaguanine plays an important role in biology, especially in the construction and modification of nucleic acids. It is a special base that can be used by some bacteria and fungi to replace adenine (adenine) to form different nucleosides (nucleoside) in RNA and DNA. 7-Deazaguanine also has applications in the development of fungal antibiotics and anticancer drugs.
In the preparation method, 7-deazaguanine can be prepared by chemical synthesis. A common method is to synthesize the target product by tandem reaction using the corresponding pyrrole reagent as the starting material.
In terms of safety information, due to the professional application of 7-deazaguanine in the laboratory, the relevant toxicity and safety information has not been fully studied and understood. Therefore, when using or handling, it is necessary to follow the corresponding safety procedures and take necessary personal protective measures, such as wearing gloves and protective glasses. When handling chemicals, direct contact with the skin and inhalation of its dust should be avoided.
Last Update：2024-04-10 22:30:50
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Product Name: Pemetrexed Impurity 71 Visit Supplier Webpage Request for quotationCAS: 7355-55-7
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 7-Deazaguanine Visit Supplier Webpage Request for quotation
CAS: 7355-55-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 7355-55-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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